Sneed's Feed & Seed is a fictional convenience store from the animated television series The Simpsons. It sells seeds, candy and many other products.
It's first and only apperance was in Season 11 episode "E-I-E-I-(Annoyed Grunt)"

The sign is a subtle joke and innuendo. The shop is called "Sneed's Feed & Seed", where feed and seed both end in the sound "-eed", thus rhyming with the name of the owner, Sneed. The sign says that the shop was "Formerly Chuck's", implying that the two words beginning with "F" and "S" would have ended with "-uck", rhyming with "Chuck". So, when Chuck owned the shop, it would have been called "Chuck's Fuck and Suck".

It is commonly reposted in Simpson related threads on 4chan as a Meme.