Lacus Clyne (ラクス・クライン Rakusu Kurain) is a fictional character introduced in the Japanese science fiction anime television series Mobile Suit Gundam SEED and appearing in the sequel Mobile Suit Gundam SEED Destiny, both part of the Gundam franchise by Sunrise. In the start of Mobile Suit Gundam SEED, Lacus is a good natured and popular female vocalist from the space colony PLANT. Born as a genetically enhanced human, Coordinator, Lacus is introduced when she is found in space by the Archangel, a ship of regular humans, the Naturals. Late in the war between the races of Coordinators and Naturals, Lacus becomes the co-leader of the Clyne Faction, joining with the battle ship the Archangel to stop both sides from fighting. Lacus is voiced in the Japanese series by Rie Tanaka. In the English adaptation, Chantal Strand is her regular voice actress, while Jillian Michaels does her singing voice.

Lacus' character has also appeared in different adaptations from Gundam SEED and Gundam SEED Destiny, as well as various video games. Her character has been popular in Japan, appearing at the top of Animage's Anime Grand Prix polls four times in the category of most popular female anime characters. She has also appeared in other popularity polls from Sunrise and other magazines. Moreover, publications for manga, anime and other media have commented on Lacus' character, giving her praise; speculations regarding her role in the series were made, but in the end it was found surprising.