Neferpitou (ネフェルピトー, Neferupitō), also known as "Pitou" (ピトー, Pitō), is a kemonomimi-themed (cat-humanoid) Chimera Ant and the firstborn of the Royal Guards. They were personally named by the Queen, as were the other Royal Guards. Like Menthuthuyoupi, Neferpitou appeared to have no memories of their previous life, if they had one. They also served as one of the main antagonists of the Chimera Ant arc first appearing when Rammot and Peggy look for the missing rare prey, Pokkle, in the Chimera Ant nest in NGL. They are also one of the first Chimera Ants to fully utilize Nen with enough skill to be recognized by even Netero as a superior combatant.

Neferpitou was very loyal to the King and would sacrifice themself for him. Of the three Royal Guards, Pitou was the most curious and would get distracted easily and loved to play, and according to Shaiapouf, would get carried away when having fun. Pitou was a cat Chimera Ant, and like a cat, loved to play with their opponents like a cat would with their prey. Despite their cheerful and playful manner though, Pitou had a cruel and terrifying personality as well.